Growth hormone — hormone replacement for the somatopause?

Human Clinical2000review (clinical endocrinology)HGH Somatropin

Toogood AA. · Hormone Research

Abstract / Summary

Reviews evidence on age-related decline of the GH/IGF-1 axis and assesses whether GH replacement is justified in older adults without documented deficiency, concluding that benefits in healthy older adults do not outweigh risks.

Methods

Investigated as a review (clinical endocrinology) in the field of endocrine research. The study design follows the methodology described in the published manuscript indexed under the identifiers listed above. Full methodological detail is available in the source publication via the PubMed or DOI link.

Results

Reviews evidence on age-related decline of the GH/IGF-1 axis and assesses whether GH replacement is justified in older adults without documented deficiency, concluding that benefits in healthy older adults do not outweigh risks.

Limitations

Narrative review; does not provide new clinical trial data.

External links