Effects of human growth hormone in men over 60 years old.

Six months of recombinant human growth hormone in healthy men over 60 increased lean body mass and reduced adipose tissue, the landmark observation that triggered subsequent investigation of GH in age-related body composition change.

Investigated as a clinical trial (older men, 6 months) in the field of endocrine research. The study design follows the methodology described in the published manuscript indexed under the identifiers listed above. Full methodological detail is available in the source publication via the PubMed or DOI link.

Six months of recombinant human growth hormone in healthy men over 60 increased lean body mass and reduced adipose tissue, the landmark observation that triggered subsequent investigation of GH in age-related body composition change.

Short duration, small sample, no long-term safety follow-up; subsequent literature has highlighted significant adverse effects (oedema, arthralgia, glucose intolerance) limiting any anti-ageing application.

• · PubMed: PMID 2355952 ↗
• · DOI: 10.1056/NEJM199007053230101 ↗
• · PubMed search by title: pubmed.ncbi.nlm.nih.gov ↗
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