Unnatural growth hormone-releasing peptide begets natural ghrelin.

Account by the discoverer of the GHRP series describing how the synthetic hexapeptide GHRP-6 led to identification of the endogenous ghrelin/GHS-R axis, establishing GHRP-6 as the prototype growth hormone secretagogue.

Investigated as a review (historical pharmacology) in the field of endocrine research. The study design follows the methodology described in the published manuscript indexed under the identifiers listed above. Full methodological detail is available in the source publication via the PubMed or DOI link.

Account by the discoverer of the GHRP series describing how the synthetic hexapeptide GHRP-6 led to identification of the endogenous ghrelin/GHS-R axis, establishing GHRP-6 as the prototype growth hormone secretagogue.

Narrative review; no original experimental data.

• · PubMed: PMID 11297568 ↗
• · DOI: 10.1210/jcem.86.4.7431 ↗
• · PubMed search by title: pubmed.ncbi.nlm.nih.gov ↗
• · Google Scholar: scholar.google.com ↗