Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin.
Tannenbaum GS, Bowers CY. · Endocrine
Synthesises evidence that GHRP-6 and related secretagogues act synergistically with endogenous GHRH and functionally antagonise somatostatin tone, accounting for the amplified GH pulse observed with combined administration.
Investigated as a review (endocrine physiology) in the field of endocrine research. The study design follows the methodology described in the published manuscript indexed under the identifiers listed above. Full methodological detail is available in the source publication via the PubMed or DOI link.
Synthesises evidence that GHRP-6 and related secretagogues act synergistically with endogenous GHRH and functionally antagonise somatostatin tone, accounting for the amplified GH pulse observed with combined administration.
Mechanistic review; does not address chronic dosing safety.
- · PubMed: PMID 11322498 ↗
- · DOI: 10.1385/ENDO:14:1:021 ↗
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