Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin.

Limited Human2001review (endocrine physiology)GHRP-6

Tannenbaum GS, Bowers CY. · Endocrine

Abstract / Summary

Synthesises evidence that GHRP-6 and related secretagogues act synergistically with endogenous GHRH and functionally antagonise somatostatin tone, accounting for the amplified GH pulse observed with combined administration.

Methods

Investigated as a review (endocrine physiology) in the field of endocrine research. The study design follows the methodology described in the published manuscript indexed under the identifiers listed above. Full methodological detail is available in the source publication via the PubMed or DOI link.

Results

Synthesises evidence that GHRP-6 and related secretagogues act synergistically with endogenous GHRH and functionally antagonise somatostatin tone, accounting for the amplified GH pulse observed with combined administration.

Limitations

Mechanistic review; does not address chronic dosing safety.

External links