Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo.

Intranasal Selank altered BDNF mRNA and protein in the rat hippocampus, providing a candidate molecular substrate (neurotrophic signalling) for its reported anxiolytic and nootropic-like effects.

Investigated as a preclinical (rat, intranasal) in the field of neuroscience research. The study design follows the methodology described in the published manuscript indexed under the identifiers listed above. Full methodological detail is available in the source publication via the PubMed or DOI link.

Intranasal Selank altered BDNF mRNA and protein in the rat hippocampus, providing a candidate molecular substrate (neurotrophic signalling) for its reported anxiolytic and nootropic-like effects.

Rodent model; no human pharmacodynamic confirmation.

• · PubMed: PMID 18841804 ↗
• · DOI: 10.1134/s0012496608040066 ↗
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