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MOTS-c: a novel mitochondrial-derived peptide regulating metabolism

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Lee et al. · PubMed

PubMed · PMID 25738459 DOI 10.1016/j.cmet.2015.02.009 PMC · PMC4350682 Search PubMed Google Scholar
Abstract / Summary

Early synthesis defining the compound as a distinct messenger bridging mitochondrial function with organismal level metabolic outcomes.

Methods

Investigated as a review in the field of metabolic research. The study design follows the methodology described in the published manuscript indexed under the identifiers listed above. Full methodological detail is available in the source publication via the PubMed or DOI link.

Results

Early synthesis defining the compound as a distinct messenger bridging mitochondrial function with organismal level metabolic outcomes.

Limitations

Largely restricted to defining foundational biological hypotheses based on cell models.

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