TB-500
TB-500 is investigated in relation to thymosin beta-4 processes like cell migration and angiogenesis. Current literature evaluates its experimental applications in preclinical tissue repair models.
PreclinicalTissue & Recovery ResearchRegenerative Biology
Formula
C₂₁₂H₃₅₀N₅₆O₇₈S
MW
4963.4 g/mol (full Tβ4)
Half-life
≈2–3 h (preclinical, plasma)
Studies
2
Research Material · Uptide.eu
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Research overview
In research contexts, TB-500 is systematically linked to thymosin beta-4-dependent cellular processes, particularly actin binding, cell migration, angiogenesis, and tissue recovery. The scientific literature primarily focuses on preclinical models investigating dermal wound healing, corneal damage, myocardial injury repair, and musculoskeletal tissue regeneration. Hair follicle biology and local inflammatory pathways are also active areas of investigation. Importantly, much of the published literature pertains to the naturally occurring thymosin beta-4 peptide rather than specific commercial TB-500 preparations. For systemic application in humans, the clinical evidentiary base remains limited.
Synonyms
Thymosin Beta-4 fragment, TB4
Classification
Synthetic thymosin beta-4 analog
Molecular weight
4963.4 g/mol (full Tβ4)
Molecular formula
C₂₁₂H₃₅₀N₅₆O₇₈S
CAS Number
77591-33-4
Half-life
≈2–3 h (preclinical, plasma)
Evidence level
Preclinical
Research areas
Tissue & Recovery Research, Regenerative Biology
Pathways
Actin-binding pathways, Cell migration signalling
Related compounds
Frequently co-cited in the literature
Research disclaimer
All information is provided for educational and scientific research purposes only. No content constitutes medical advice, treatment recommendations, administration guidance or dosing recommendations. Products referenced are intended for laboratory and analytical research.