Compounds/Synthetic melanocortin analog

Melanotan-II

Melanotan-II is studied as an experimental analog of alpha-melanocyte-stimulating hormone. Current evidence investigates its potent multi-receptor activation relating to melanin production, energy homeostasis, and central nervous mechanisms.

MixedDermatological ResearchMetabolic Research
Formula
C₅₀H₆₉N₁₅O₉
MW
1024.18 g/mol
Half-life
≈33 min (literature, plasma)
Studies
2
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Research overview
Melanotan-II is a synthetic, structurally non-selective analog of the naturally occurring peptide hormone alpha-MSH. The scientific literature comprehensively targets its activation of central and peripheral melanocortin receptors, focusing specifically on functional pathways driving substantial melanin production and epidermal pigmentation parameters. Furthermore, Melanotan-II is vigorously investigated inside experimental frameworks concerning the modulation of sexual function, central appetite suppression, overarching energy homeostasis, and corresponding neurobiological melanocortin cascades. The extant literature underscores the broad involvement of this expansive receptor family in diverse behavioral paradigms and systemic inflammatory responses. Concurrently, medical literature continuously addresses persistent safety parameters linked strictly to unregulated phase exploration.
Synonyms
MT-II, MT2
Classification
Synthetic melanocortin analog
Molecular weight
1024.18 g/mol
Molecular formula
C₅₀H₆₉N₁₅O₉
CAS Number
121062-08-6
Half-life
≈33 min (literature, plasma)
Evidence level
Mixed
Research areas
Dermatological Research, Metabolic Research
Pathways
Melanocortin receptor (MC1R-MC5R) pathways, Central nervous signalling

Related compounds

Frequently co-cited in the literature

Research disclaimer

All information is provided for educational and scientific research purposes only. No content constitutes medical advice, treatment recommendations, administration guidance or dosing recommendations. Products referenced are intended for laboratory and analytical research.