Ipamorelin
Ipamorelin is investigated as a highly selective growth hormone secretagogue. Research evaluates its ability to stimulate physiological GH release with minimal disruption to collateral hormonal pathways.
PreclinicalEndocrine Research
Formula
C₃₈H₄₉N₉O₅
MW
711.86 g/mol
Half-life
≈2 h (literature)
Studies
2
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Research overview
Ipamorelin is a synthetic pentapeptide investigated strictly as a selective growth hormone secretagogue. Researchers study its efficacy as an agonist within the ghrelin/growth hormone secretagogue receptor (GHSR) system, with particular attention to hormonal selectivity. A prominent characteristic documented in pharmacological studies is that ipamorelin stimulates robust GH secretion while exerting significantly less influence on adrenocorticotropic hormone (ACTH) and cortisol levels compared to earlier generations of GHRPs. Concurrently, ipamorelin is investigated in experimental models regarding gastrointestinal motility and postoperative recovery markers. Its clinical application is not broadly established, with current knowledge localized to foundational pharmacological observation.
Synonyms
NNC 26-0161
Classification
Pentapeptide growth hormone secretagogue
Molecular weight
711.86 g/mol
Molecular formula
C₃₈H₄₉N₉O₅
CAS Number
170851-70-4
Half-life
≈2 h (literature)
Evidence level
Preclinical
Research areas
Endocrine Research
Pathways
GHSR signalling, Enteric neural pathways
Related compounds
Frequently co-cited in the literature
Research disclaimer
All information is provided for educational and scientific research purposes only. No content constitutes medical advice, treatment recommendations, administration guidance or dosing recommendations. Products referenced are intended for laboratory and analytical research.