Compounds/Copper-binding tripeptide

GHK-Cu

GHK-Cu is a copper-chelating tripeptide frequently investigated within cutaneous biology. Researchers systematically evaluate its impact on cellular matrix remodeling, dermal repair models, and generalized antioxidant responses.

MixedDermatological ResearchRegenerative Biology
Formula
C₁₄H₂₃CuN₆O₄ (chelated)
MW
402.92 g/mol
Half-life
≈1–2 h (literature)
Studies
2
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Research overview
GHK-Cu is a copper-chelating tripeptide that is relatively extensively documented in scientific literature pertaining strictly to skin biology and investigational wound healing contexts. Researchers critically evaluate processes encompassing collagen and elastin genesis, targeted extracellular matrix (ECM) remodeling, local inflammatory modulation, antioxidant pathway responses, and corresponding gene expression networks. Within broader dermatological and regenerative literature, GHK-Cu is primarily discussed regarding models of in vitro dermal aging, epidermal skin barrier protection, and foundational hair follicle biology. While secondary hypotheses explore regenerative capacities within other systemic networks, the definitive research focus remains solidly localized to topical tissue repair, with claims maintained strictly within experimental boundaries.
Synonyms
Copper tripeptide-1, GHK-Cu(II)
Classification
Copper-binding tripeptide
Molecular weight
402.92 g/mol
Molecular formula
C₁₄H₂₃CuN₆O₄ (chelated)
CAS Number
89030-95-5
Half-life
≈1–2 h (literature)
Evidence level
Mixed
Research areas
Dermatological Research, Regenerative Biology
Pathways
Matrix metalloproteinase (MMP) signalling, Antioxidant/Superoxide dismutase pathways

Related compounds

Frequently co-cited in the literature

Research disclaimer

All information is provided for educational and scientific research purposes only. No content constitutes medical advice, treatment recommendations, administration guidance or dosing recommendations. Products referenced are intended for laboratory and analytical research.